Migraine and Repeated Stressors

"Migraine offers a unique model to understand the consequences of repeated stressors on the brain." "...the effects of repeated stress may lead to alteration in brain networks both functionally and structurally." "As a result the brain responds abnormally to environmental conditions (psychological or physiological). Here we present an alternative perspective on migraine disease and propose that changes in brain states may occur as a result of repeated migraine attacks through maladaptive coping mechanisms." Headache. 2012 Oct; 52(Suppl 2): 102–106. (https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3475609/)

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